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Southeastern Clinical Research Institute

Serious kidney science. Proven results.

The region's premier site for kidney studies. Trials in Augusta, Georgia for more than 25 years, run by the same board-certified nephrologists who care for the CSRA every day. Study care is provided at no cost, and your insurance is never billed.

For Referring Physicians

Refer a patient. Keep the loop closed.

Send us a patient for a research evaluation and you stay informed at every step. We confirm eligibility, manage all study-related care, and report back to you directly.

For Sponsors & CROs

A proven kidney site, feasibility to closeout.

Phase 1b, Phase 2a, Phase 2b, and Phase 3 trials inside the largest private-practice nephrology group in the CSRA: board-certified investigators, GCP-trained and ACRP-certified coordinators, a dedicated regulatory specialist, on-site pharmacy and lab, and your central IRB accepted.

Clinical studies conducted
Years conducting clinical research
Physician investigators: every NAPC nephrologist
Therapeutic areas studied
Where Care Meets Research

We practice medicine, and help write it.

For more than 25 years the nephrologists of Nephrology Associates, PC have served as principal and site investigators on the trials that define modern kidney care: SPRINT, DAPA-CKD, the vadadustat anemia program. They brought those therapies to the people of the CSRA first. Southeastern Clinical Research Institute is where that work happens: the region's premier site for kidney studies, run to the standard sponsors expect of a national center of excellence.

  • Investigators published in the New England Journal of Medicine
  • The largest private-practice nephrology population in the CSRA, across seven offices
  • Trusted by Eli Lilly, AstraZeneca, Bayer, Novo Nordisk, Novartis, GSK, Merck, and Amgen
  • A dedicated research facility in Augusta's medical district: on-site pharmacy and lab, private monitor space
  • Phase 1b, Phase 2a, Phase 2b, and Phase 3 trials, 200+ studies and counting
Inside SCRI

The research institute, in motion

1521 Anthony Road in Augusta's medical district: a dedicated research site, its laboratory, and the team that runs every study.

Southeastern Clinical Research Institute · Augusta, Georgia
Enrolling Now

Studies open today

Three studies are open to enrollment in Augusta, two more are opening soon, and five are under way with enrollment closed. Eligibility is confirmed by our study team.

Enrolling now

Primary FSGS

Praliciguat · Phase 2 · NCT07268638

Praliciguat, an oral sGC stimulator, in adults with primary focal segmental glomerulosclerosis whose protein leak persists on a maximally tolerated ACE inhibitor or ARB.

Who it is forAdults with biopsy-confirmed primary FSGS, a urine protein-to-creatinine ratio of 1 g/g or more on a maximally tolerated ACE inhibitor or ARB, and eGFR of 25 or above.

Enrolling now

APOL1-Mediated Kidney Disease

AZD2373 · Phase 2 · NCT06824987

AZD2373 in adults with APOL1-mediated kidney disease (AMKD) who carry two high-risk APOL1 variants (G1 and G2), measured by the change in urine albumin at 30 weeks (APPRECIATE).

Who it is forAdults 18 to 70 of African descent with a high-risk APOL1 genotype, a urine albumin-to-creatinine ratio of 300 mg/g or more, and eGFR of 25 or above.

Enrolling now

Elevated Lipoprotein(a)

Muvalaplin · Phase 3 · NCT07157774

Muvalaplin, an oral lipoprotein(a) inhibitor, for reducing heart attack and stroke risk in adults with high Lp(a) who have cardiovascular disease or are at risk of a first event (MOVE-Lp(a)).

Who it is forAdults with Lp(a) of 175 nmol/L or more who have had a cardiovascular event, or are at high risk of one, including reduced kidney function with diabetes.

Opening soon

Two more studies are in start-up. Ask now and the study team will keep you in mind for screening.

NovartisPolycystic Kidney Disease (ADPKD)Farabursen · Phase 3 · NovartisOpening soon Eli LillyObesity with Type 2 DiabetesEloralintide · Phase 3 · Eli LillyOpening soon
Our Investigators

Led by Dr. Matthew Diamond, DO, FASN, FACP

Every SCRI investigator is a practicing, board-certified nephrologist at Nephrology Associates, PC: the same physicians our patients see in clinic, and the authors behind the evidence.

Dr. Matthew Diamond, DO, FASN, FACP
Medical Director & Chief Scientific Officer · Southeastern Clinical Research Institute

Dr. Matthew DiamondDO, FASN, FACP

Former Professor of Medicine at the Medical College of Georgia and a SPRINT site investigator, published in the New England Journal of Medicine on intensive blood-pressure control and chronic kidney disease. A Fellow of both the American Society of Nephrology and the American College of Physicians, he directs every study SCRI runs.

“Research here is not separate from care. It is an extension of it.”
Barton Brezina, MD
President & Managing Partner, NAPC

Barton BrezinaMD

H. Doug Hubert, MD
Investigator

H. Doug HubertMD

Devesh Patel, MD
Investigator

Devesh PatelMD

S. Nabil Babar, MD
Investigator

S. Nabil BabarMD

Ryan Altenburg, DO
Investigator

Ryan AltenburgDO

James Stenard, MD, MS
Investigator

James StenardMD, MS

Michael B. Whitlow, MD
Investigator

Michael B. WhitlowMD

Nadeem Afzal, MD
Investigator

Nadeem AfzalMD

Trevor Tobin, DO
Investigator

Trevor TobinDO

What We Study

Therapeutic areas

Our investigators concentrate on the conditions that drive the greatest burden of kidney disease across the Southeast.

Chronic Kidney Disease

Disease-modifying therapies aimed at slowing progression and protecting function across CKD stages.

Diabetic Kidney Disease

Agents that protect the diabetic kidney, including SGLT2 and non-steroidal MRA pathways.

Cardiorenal Protection

Studies at the intersection of heart and kidney disease, including elevated lipoprotein(a) and obesity outcomes.

Glomerular Disease

Investigational therapy for IgA nephropathy, lupus nephritis, and other immune-mediated kidney disease.

Anemia & Mineral Bone

Novel approaches to the anemia and mineral-bone complications of advanced kidney disease.

Hypertension

Trials targeting resistant and uncontrolled blood pressure, a principal driver of kidney decline.

Dialysis

Drug and device studies in hemodialysis and peritoneal dialysis: home hemodialysis, infection detection, anticoagulation.

Additional experience across dialysis access, hyperparathyroidism, hyperphosphatemia, iron deficiency, hyperlipidemia, proteinuria, and immunology.

Who We Work With

Trusted by the sponsors writing the next chapter.

Sponsor partners over more than 25 years: global pharma, emerging biotech, and device companies.

  • Eli Lilly
  • AstraZeneca
  • Bayer
  • Novartis
  • Novo Nordisk
  • GSK
  • Merck
  • Amgen
  • Johnson & Johnson
  • Otsuka
  • Roche
  • Calliditas
  • Natera
  • Regulus
  • Mineralys
  • Quanta Dialysis
Sponsor Voice

What sponsors say

SCRI is the site you hope for on a nephrology program: investigators who see these patients every day, coordinators who know the protocol cold, and enrollment that arrives clean.

Eli Lilly and CompanyClinical Trial Manager
Advance Kidney Care

Ready to get started?

For Patients

See if a study fits

Tell us a little about your kidney health and we will call you back. It costs nothing to ask.

Start here
For Referring Physicians

Refer a patient

We screen against every open protocol and report the outcome back to your office, either way.

Refer now
For Sponsors & CROs

Bring us your protocol

Call to discuss feasibility with a site that has delivered kidney trials for more than 25 years.

Call (706) 922-3005

Southeastern Clinical Research Institute, LLC · 1521 Anthony Road, Augusta, Georgia 30904 · (706) 922-3005 · Fax (706) 722-5843